This is a funny as hell video about MS Paint, made by Macenstein, a group of bored Mac users with too much time on their hands. This is the same news outlet that brought you the unspecified Pizza restaraunt that went bankrupt after moving onto Vista.

The funniest quotes from this video:
"The future is right around the corner"
"The future is now"
"The future is in the past"

Check out the 3D Pipes screensaver in the background

http://www.youtube.com/watch?v=Hxx2KcPWWZg

Now, to be fair, here's a time-lapsed YouTube video titled "How to paint the Mona Lisa with Microsoft Paint"

http://www.youtube.com/watch?v=uk2sPl_Z7ZU

Screenshot:


or this one "How to draw a car in Microsoft Paint":

http://www.youtube.com/watch?v=ElrldD02if0

Screenshot:


He might have been using a PC pen but either way it just goes to show that it's all about the artist's talent rather than about the software.

I cannot agree with you more - it definitely is how much one practices. For a creative outlet the different software are just tools.